Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24697655 | 0.77 | SLC6A2 (0.46) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL9148305 | 0.76 | — | — | |
| SCHEMBL2828716 | 0.73 | HTR1A (0.36) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL22664822 | 0.71 | NQO2 (0.39) | KMT2AMEN1MAPK1 | |
| SCHEMBL16334980 | 0.70 | SLC6A2 (0.44) | KMT2ATHRATHRBMEN1LMNA | |
| SCHEMBL31535455 | 0.70 | SLC6A2 (0.44) | KMT2ATHRATHRBHTR1ASLC6A2 | |
| SCHEMBL2404772 | 0.67 | HRH1 (0.43) | KMT2ALMNAHTR1ASLC6A2SLC6A3 | |
| SCHEMBL14915542 | 0.67 | HRH1 (0.43) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL31652114 | 0.67 | HRH1 (0.43) | KMT2ALMNAHTR1ASLC6A2SLC6A3 | |
| SCHEMBL737295 | 0.67 | MEN1 (0.32) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |