Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670363 | 0.88 | ALDH1A1 (0.42) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL16965305 | 0.86 | POLB (0.52) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL27721600 | 0.82 | SMN1; SMN2 (0.46) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL28586050 | 0.81 | SMN1; SMN2 (0.68) | POLBLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL17093002 | 0.81 | SMN1; SMN2 (0.46) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL1826048 | 0.81 | SMN1; SMN2 (0.67) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL11492059 | 0.81 | SMN1; SMN2 (0.67) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL10534503 | 0.81 | SMN1; SMN2 (0.45) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL7320984 | 0.81 | POLB (0.45) | POLBLMNASMN1; SMN2ALDH1A1ATM | |
| SCHEMBL7838421 | 0.81 | SMN1; SMN2 (0.67) | POLBLMNASMN1; SMN2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641895-A | Indole compounds substituted with [1, 2, 4] triazolo [1, 5-a ] pyridyl | 百时美施贵宝公司 | 2019-04-16 | — | — | CN | disclosed |