Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719895 | 0.76 | — | — | |
| SCHEMBL10835472 | 0.76 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL10836020 | 0.72 | ALDH1A1 (0.44) | TSHRLMNAALOX15 | |
| SCHEMBL13484758 | 0.71 | DPP4 (0.32) | — | |
| SCHEMBL13485080 | 0.71 | — | — | |
| SCHEMBL16061080 | 0.70 | — | — | |
| SCHEMBL9265602 | 0.70 | TSHR (0.46) | TSHRLMNAALOX15BLMCHRM2 | |
| SCHEMBL27389152 | 0.70 | TSHR (0.32) | TSHR | |
| SCHEMBL10835955 | 0.69 | NPC1 (0.33) | TSHR | |
| SCHEMBL17224246 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651424-A | A kind of simple synthesis of 7- protecting group -4- (1- hydrogen-pyrazoles -4- base) pyrroles [2,3-d] pyrimidine | 新发药业有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109651424-A | A kind of simple synthesis of 7- protecting group -4- (1- hydrogen-pyrazoles -4- base) pyrroles [2,3-d] pyrimidine | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651424-A | A kind of simple synthesis of 7- protecting group -4- (1- hydrogen-pyrazoles -4- base) pyrroles [2,3-d] pyrimidine | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |