Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176512 | 1.00 | HRH1 (0.55) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL6544199 | 0.89 | CHRM2 (0.55) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL13036601 | 0.87 | HRH1 (0.48) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL2622207 | 0.80 | HRH1 (0.55) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL2622209 | 0.78 | CHRM2 (0.59) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL2622208 | 0.78 | CHRM2 (0.59) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL8260622 | 0.78 | CHRM2 (0.59) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL7626977 | 0.78 | KMT2A (0.53) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL10426198 | 0.76 | CACNA1F (0.52) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL13950534 | 0.73 | CACNA1F (0.53) | HRH1CACNA1FCHRM2CHRM1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666160-A | A kind of dynamic aggregation object with hybrid cross-linked network | 翁秋梅 | 2019-04-23 | — | — | CN | disclosed |