Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357803 | 0.83 | KMT2A (0.46) | KMT2ASLC6A4ATML3MBTL1MEN1 | |
| SCHEMBL14261318 | 0.83 | KMT2A (0.46) | KMT2ASLC6A4ATML3MBTL1MEN1 | |
| SCHEMBL28772271 | 0.83 | KMT2A (0.56) | KMT2ACHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL13380255 | 0.81 | KMT2A (0.55) | KMT2AL3MBTL1MEN1LMNAPTGS1 | |
| SCHEMBL9543022 | 0.81 | KMT2A (0.58) | KMT2ASLC6A3MEN1LMNAPTGS1 | |
| SCHEMBL12069800 | 0.80 | CTSK (0.49) | KMT2AATMMAPT | |
| SCHEMBL6784979 | 0.80 | CTSK (0.49) | KMT2AATMMAPT | |
| SCHEMBL12068193 | 0.80 | CTSK (0.49) | KMT2AATMMAPT | |
| SCHEMBL31477299 | 0.80 | KMT2A (0.53) | KMT2ACACNA1CMEN1LMNAPTGS1 | |
| SCHEMBL16871126 | 0.79 | KMT2A (0.51) | KMT2AMEN1PTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741716-B1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5821363-A | Antineoplastic use and pharmaceutical compositions containing them | PHARMACIA & UPJOHN COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0741716-A1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020582-A1 | Δ12,13-ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |