Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.68 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167781 | 1.00 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3279911 | 0.98 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL30624762 | 0.83 | SIGMAR1 (0.71) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL21243273 | 0.83 | SIGMAR1 (0.73) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Methamphetamine SCHEMBL42615 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Methamphetamine SCHEMBL4781849 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Methamphetamine SCHEMBL13747483 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Methamphetamine SCHEMBL20211416 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Methamphetamine SCHEMBL15094315 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| Levmetamfetamine SCHEMBL727412 | 0.81 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115379759-A | Pest control method, pest control agent composition, and pest control agent set | 日本曹达株式会社 | 2022-11-22 | — | — | CN | claimed |
| EP-1807102-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND SEXUAL DYSFUNCTION | Merck & Co., Inc. (US) | 2007-07-18 | — | — | EP | claimed |
| WO-2006049933-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND SEXUAL DYSFUNCTION | MERCK & CO., INC. (US) | 2006-05-11 | — | — | WO | claimed |
| US-20250171395-A1 | PROCESS FOR THE PREPARATION OF AMPHETAMINE AND DERIVATIVES THEREOF | GRANULES INDIA LIMITED (IN) | 2025-05-29 | — | — | US | disclosed |
| EP-4304576-A1 | COMPOSITIONS COMPRISING ENZYME-CLEAVABLE PRODRUGS AND CONTROLLED RELEASE NAFAMOSTAT AND METHODS OF USE THEREOF | Ensysce Biosciences, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-107787322-B | Tricyclic compounds and their use as phosphodiesterase inhibitors | 辉瑞大药厂 | 2023-07-07 | — | — | CN | disclosed |
| CN-107426999-B | Pyridine amide compounds having fungicidal activity | 美国陶氏益农公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115515962-A | Fused isoxazoline derivatives and their use as herbicides | 巴斯夫欧洲公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115460923-A | Glufosinate formulations containing amines or ammonium salts | 巴斯夫欧洲公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115461435-A | Alkyl polyamine polyglycerol surfactants | 诺力昂化学品国际有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111909053-B | Diarylamine unit-based amide derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2022-12-06 | — | — | CN | disclosed |
| US-5389638-A | Nervous system disorders | ABBOTT LABORATORIES (US) | 1995-02-14 | — | — | US | disclosed |
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5288749-A | Treating central nervous system or cardiovascular disorders | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1993012754-A2 | TERTIARY AND SECONDARY AMINES AS ALPHA-2 ANTAGONISTS AND SEROTONIN UPTAKE INHIBITORS | ABBOTT LABORATORIES (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0507863-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | — | 1993-07-07 | — | — | EP | disclosed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | disclosed |
| EP-0507863-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5120641-A | Incubating with sample, determining radioactivity | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171395-A1 | PROCESS FOR THE PREPARATION OF AMPHETAMINE AND DERIVATIVES THEREOF | COMT, DDT, DBH | SIGMAR1 47/4885TAAR1 43/4885SLC18A2 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.