Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24144238 | 0.90 | NR4A2 (0.64) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28289130 | 0.84 | CFTR (0.54) | GABRA1GABRB2GABRB1GABRA3KDM4E | |
| SCHEMBL28287817 | 0.84 | KDM4E (0.71) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28287772 | 0.83 | F7 (0.59) | NR4A2KDM4EHSD17B10 | |
| SCHEMBL28289143 | 0.83 | KDM4E (0.69) | GABRA1GABRB2GABRB1GABRA3KDM4E | |
| SCHEMBL27795085 | 0.82 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL2979894 | 0.82 | KDM4E (0.68) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28287753 | 0.82 | MEN1 (0.59) | GABRA1GABRB2KDM4EHSD17B10 | |
| SCHEMBL28289156 | 0.82 | HSD17B10 (0.56) | GABRA1GABRB2GABRB1GABRA3KDM4E | |
| SCHEMBL28872023 | 0.81 | KDM4E (0.61) | NR4A2KDM4EHSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651247-A | A kind of green high-efficient synthetic method of carbostyril compound | 云南民族大学 | 2019-04-19 | — | — | CN | disclosed |