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Sugi Predict / Compounds / Methacrylic Acid

Methacrylic Acid

Methacrylic Acid

SCHEMBL28289356

C=C(C)C#N.C=C(C)C(=O)O.C=C(C)C(=O)OCCCC.C=COC(C)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.50
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ THRB P10828 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ TP53 P04637 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ HCAR2 Q8TDS4 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28274680 0.99 TSHR (0.49) TSHRALDH1A1HPGDTHRBPOLB
Methacrylic Acid SCHEMBL28274679 0.89 TSHR (0.45) TSHRALDH1A1HPGDTHRBPOLB
SCHEMBL6744183 0.88 TSHR (0.64) TSHRALDH1A1HPGDTHRBPOLB
SCHEMBL9562635 0.85 TSHR (0.68) TSHRALDH1A1HPGDTHRBPOLB
SCHEMBL28471522 0.82 TSHR (0.75) TSHRALDH1A1HPGDTHRBPOLB
SCHEMBL11525707 0.82 TSHR (0.75) TSHRALDH1A1HPGDTHRBPOLB
SCHEMBL28149809 0.82 TSHR (0.75) TSHRALDH1A1HPGDTHRBPOLB
Methacrylic Acid SCHEMBL8956980 0.80 TSHR (0.66) TSHRALDH1A1HPGDTHRBPOLB
Acrylic Acid SCHEMBL4579288 0.80 TSHR (0.67) TSHRALDH1A1HPGDTHRBPOLB
Methacrylic Acid SCHEMBL8427966 0.80 TSHR (0.75) TSHRALDH1A1HPGDTHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109665203-A Tubular package 旭化成株式会社 2019-04-23 — — CN disclosed