Methacrylic Acid

Methacrylic Acid

SCHEMBL8956980

C=C(C)C(=O)O.C=C(C)C(=O)OCCCC.C=CC=C

nearest known ligand 0.66

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.66
HPGD P15428 1/20 0.50
THRB P10828 1/20 0.49
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
ATM Q13315 1/20 0.44
HCAR2 Q8TDS4 3/20 0.43
NAAA Q02083 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
RAD52 P43351 1/20 0.34
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL4285807 0.95 TSHR (0.72) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL8427966 0.93 TSHR (0.75) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL462262 0.93 TSHR (0.75) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL9422682 0.93 TSHR (0.75) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL8406971 0.93 TSHR (0.75) TSHRHPGDTHRBALDH1A1TDP1
Acrylic Acid SCHEMBL17746699 0.92 TSHR (0.64) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL29038218 0.91 TSHR (0.72) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL28398525 0.89 TSHR (0.70) TSHRHPGDTHRBALDH1A1TDP1
Methacrylic Acid SCHEMBL7908009 0.89 TSHR (0.69) TSHRHPGDTHRBALDH1A1TDP1
Butadiene SCHEMBL28265841 0.88 TSHR (0.64) TSHRHPGDTHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4367323-A Production of hydrogels SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-04 US claimed
CN-109054270-A A kind of modified poly (methyl methacrylate) composition and preparation method thereof, application 金凯新 2018-12-21 CN disclosed
EP-0472362-B1 Process for the production of highly water absorptive polymers MITSUBISHI CHEM CORP (JP) 1996-01-10 EP disclosed
US-5202400-A Emulsion polymerization of unsaturated monomers yields large free-flowing water swellable particles MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-04-13 US disclosed
EP-0472362-A1 Process for the production of highly water absorptive polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-02-26 EP disclosed
US-4367323-A Production of hydrogels SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-04 US disclosed