Naphthalene

Naphthalene

SCHEMBL28289682

CO[Si](OC)OC.c1ccc2ccccc2c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.50
ALOX12 P18054 1/20 0.50
CYP1A2 P05177 4/20 0.46
NQO1 P15559 1/20 0.39
CA4 P22748 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
NQO2 P16083 4/20 0.37
MAPT P10636 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CDK5 Q00535 1/20 0.34
CDK5R1 Q15078 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL8679262 0.79 CYP2A6 (0.67) CYP2A6ALOX12CYP1A2NQO1CA4
Toluene SCHEMBL28193163 0.77 ACHE (0.61) ALOX12CA4CA12CA1CA2
Naphthalene SCHEMBL3263116 0.76 CYP2A6 (0.61) CYP2A6ALOX12CYP1A2NQO1CA4
Benzene SCHEMBL28147226 0.75 CA4 (0.32) CA4
Naphthalene SCHEMBL14954153 0.71 CYP2A6 (0.80) CYP2A6ALOX12CYP1A2CA1CA2
Naphthalene SCHEMBL1451946 0.71 CYP2A6 (0.80) CYP2A6ALOX12CYP1A2CA1CA2
Naphthalene SCHEMBL14954383 0.71 CYP2A6 (0.80) CYP2A6ALOX12CYP1A2CA1CA2
Naphthalene SCHEMBL1331142 0.71 CYP2A6 (1.00) CYP2A6ALOX12CYP1A2CA1CA2
Naphthalene SCHEMBL1332240 0.71 CYP2A6 (1.00) CYP2A6ALOX12CYP1A2CA1CA2
Naphthalene SCHEMBL8613802 0.71 CYP2A6 (1.00) CYP2A6ALOX12CYP1A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946154-A Organic silicon resin monomer containing large steric hindrance functional group, preparation method thereof and application of high-temperature-resistant material 哈尔滨工业大学 2024-04-30 CN disclosed
CN-109716491-A The manufacturing method of field effect transistor and the manufacturing method of wireless telecom equipment 东丽株式会社 2019-05-03 CN disclosed