SCHEMBL2828996

SCHEMBL2828996

CC(C)(C)[Si](C)(C)OCCOCCOCCOCCBr

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7739878 1.00 DUT (0.41) DUT
SCHEMBL7197606 1.00 DUT (0.41) DUT
SCHEMBL30378662 0.88 DUT (0.36) DUT
SCHEMBL57968 0.86 DUT (0.34) DUT
SCHEMBL925192 0.84 DUT (0.37) DUT
SCHEMBL11580466 0.81 DUT (0.42) DUT
SCHEMBL29284186 0.80 DUT (0.41) DUT
SCHEMBL30612911 0.80 DUT (0.41) DUT
SCHEMBL26510570 0.80 DUT (0.41) DUT
SCHEMBL20088142 0.80 DUT (0.41) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599672-B2 KRAS proteolysis targeting chimeras PAQ Therapeutics Inc. (US) 2026-04-14 US disclosed
US-20250144225-A1 KRAS Proteolysis Targeting Chimeras PAQ Therapeutics Inc. (US) 2025-05-08 US disclosed
WO-2025076044-A1 KRAS PROTEOLYSIS TARGETING CHIMERAS PAQ Therapeutics Inc. (US) 2025-04-10 WO disclosed
EP-2213652-B1 Stilbene derivatives and their use for binding and imaging amyloid plaques UNIV PENNSYLVANIA (US) 2014-10-22 EP disclosed
US-8465726-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-06-18 US disclosed
US-7858072-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-12-28 US disclosed
US-20100266500-A1 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-10-21 US disclosed
US-7807135-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-10-05 US disclosed
EP-2213652-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques The Trustees of The University of Pennsylvania (US) 2010-08-04 EP disclosed
EP-1841465-A4 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES UNIV PENNSYLVANIA (US) 2009-04-01 EP disclosed
EP-1838298-A4 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES UNIV PENNSYLVANIA (US) 2009-03-04 EP disclosed
EP-1841465-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES The Trustees of The University of Pennsylvania (US) 2007-10-10 EP disclosed
EP-1838298-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES The Trustees of The University of Pennsylvania (US) 2007-10-03 EP disclosed
US-20060269474-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-11-30 US disclosed
US-20060269473-A1 Stilbene derivatives and their use for binding and imaging amyoid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-11-30 US disclosed
WO-2006078384-A2 STILBENE DERIVATIVES AND THEIR USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-07-27 WO disclosed
WO-2006066104-A2 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060269473-A1 Stilbene derivatives and their use for binding and imaging amyoid plaques IAPP, APP, APBA1 DUT 4225/4885
US-12599672-B2 KRAS proteolysis targeting chimeras KRAS, HRAS, NRAS DUT 3908/4885
US-20250144225-A1 KRAS Proteolysis Targeting Chimeras KRAS, HRAS, NRAS DUT 3931/4885
US-20100266500-A1 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES APP, APBA1, PSEN1 DUT 3308/4885
US-20060269474-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques APP, APBA1, PSEN1 DUT 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.