Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039242 | 0.96 | CHRNB4 (0.67) | CHRNB4CHRNA3LTA4HKMT2ANR1H4 | |
| SCHEMBL29039239 | 0.96 | CHRNB4 (0.67) | CHRNB4CHRNA3LTA4HKMT2ANR1H4 | |
| SCHEMBL30344804 | 0.89 | CHRNB4 (0.61) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL30344019 | 0.85 | CHRNB4 (0.66) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL26999492 | 0.82 | CHRNB4 (0.63) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL29039262 | 0.82 | CHRNB4 (0.63) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL30575478 | 0.81 | NR1H4 (0.68) | KMT2ANR1H4 | |
| SCHEMBL931299 | 0.81 | NR1H4 (0.68) | KMT2ANR1H4 | |
| SCHEMBL3166997 | 0.80 | LTA4H (0.88) | LTA4H | |
| SCHEMBL12420676 | 0.80 | NR1H4 (0.67) | KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678815-A | N- benzyl benzamide derivatives and preparation method thereof and pharmaceutical applications | 中国药科大学 | 2019-04-26 | — | — | CN | disclosed |