SCHEMBL28290216

SCHEMBL28290216

O=C(O)c1ccccc1-c1ccoc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.49
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX12 P18054 1/20 0.47
ALDH1A1 P00352 4/20 0.46
ALOX15 P16050 1/20 0.46
GAA P10253 1/20 0.45
FOLH1 Q04609 2/20 0.44
KDM4E B2RXH2 4/20 0.42
KMT2A Q03164 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
HNF4A P41235 1/20 0.42
HTT P42858 1/20 0.41
USP2 O75604 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14397455 0.88 KDM4C (0.47) MYCCYP3A4CYP2C9ALOX12ALDH1A1
SCHEMBL27624421 0.81 KMT2A (0.42) CYP3A4ALOX12ALDH1A1ALOX15KDM4E
SCHEMBL2318775 0.81 HPGD (0.45) MYCALDH1A1KDM4EKMT2AL3MBTL1
SCHEMBL8861326 0.80 KMT2A (0.41) ALDH1A1KMT2AL3MBTL1LMNAPOLB
SCHEMBL36145 0.79 ALDH1A1 (0.72) MYCCYP3A4CYP2C9ALOX12ALDH1A1
SCHEMBL30028907 0.79 ALDH1A1 (0.72) MYCCYP3A4CYP2C9ALOX12ALDH1A1
Phthalic Acid SCHEMBL28292421 0.79 ALDH1A1 (0.58) ALDH1A1ALOX15KDM4EKMT2AL3MBTL1
SCHEMBL1549765 0.79 KMT2A (0.46) KMT2AHNF4ATSHR
SCHEMBL14398057 0.77 POLB (0.50) MYCCYP3A4CYP2C9ALOX12ALDH1A1
Hydrochloric Acid SCHEMBL10888462 0.77 ALDH1A1 (0.68) MYCCYP3A4CYP2C9ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608420-A A method of functionalization 1,3- butadiene is synthesized based on biomass chemicals 中国科学院长春应用化学研究所 2019-04-12 CN claimed
CN-109608420-A A method of functionalization 1,3- butadiene is synthesized based on biomass chemicals 中国科学院长春应用化学研究所 2019-04-12 CN disclosed