SCHEMBL28290246

SCHEMBL28290246

COC(=O)C(N)OC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
TDP1 Q9NUW8 1/20 0.34
CA14 Q9ULX7 2/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
CA12 O43570 1/20 0.31
KMT2A Q03164 1/20 0.31
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27491773 0.82 SMN1; SMN2 (0.40) ALDH1A1SMN1; SMN2CA14CA12KMT2A
SCHEMBL5967284 0.76
SCHEMBL5225767 0.75 TSHR (0.42) ALDH1A1TSHRSMN1; SMN2TDP1CA14
SCHEMBL18760226 0.75 TSHR (0.42) ALDH1A1TSHRSMN1; SMN2TDP1CA14
SCHEMBL24225951 0.74
SCHEMBL10011167 0.74 ALDH1A1 (0.47) ALDH1A1TSHRSMN1; SMN2TDP1CA14
SCHEMBL10012355 0.74 ALDH1A1 (0.47) ALDH1A1TSHRSMN1; SMN2TDP1CA14
SCHEMBL28036345 0.74
SCHEMBL10611609 0.74
SCHEMBL27781702 0.73 ALDH1A1 (0.41) ALDH1A1TSHRSMN1; SMN2TDP1CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689933-A alkaline composition for treating metal substrates PPG工业俄亥俄公司 2019-04-26 CN disclosed