Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188631 | 0.84 | AURKA (0.59) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL13363917 | 0.82 | MAPT (0.61) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL17940697 | 0.80 | KDM4E (0.60) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL29871430 | 0.80 | MAPT (0.58) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL28420428 | 0.78 | CXCR2 (0.59) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL29257205 | 0.78 | MAPT (0.56) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL29412287 | 0.77 | ESR2 (0.60) | KDM4EHPGDHTTESR2ALDH1A1 | |
| SCHEMBL222 | 0.77 | ESR2 (0.60) | KDM4EHPGDHTTESR2ALDH1A1 | |
| SCHEMBL31264026 | 0.76 | KDM4E (0.51) | KDM4EGAAMEN1MAPTKMT2A | |
| SCHEMBL6550968 | 0.76 | KDM4E (0.51) | KDM4EGAAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715615-A | Biaryl methyl heterocycles | 蒙特利尔大学 | 2019-05-03 | — | — | CN | disclosed |