Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406998 | 0.84 | CXCR2 (0.44) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL4188631 | 0.84 | AURKA (0.59) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL29642992 | 0.80 | KDM4E (0.56) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL6550968 | 0.80 | KDM4E (0.51) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL17940666 | 0.80 | KDM4E (0.56) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL17940697 | 0.80 | KDM4E (0.60) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL31264026 | 0.80 | KDM4E (0.51) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL28969955 | 0.80 | MAPT (0.65) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL28290256 | 0.78 | KDM4E (0.53) | CXCR2KDM4EGAAMEN1MAPT | |
| SCHEMBL20881623 | 0.76 | KDM4E (0.76) | CXCR2KDM4EGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393448-B | Thermal activation delayed fluorescent material and application thereof | 深圳大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111393448-A | Thermal activation delayed fluorescent material and application thereof | 深圳大学 | 2020-07-10 | — | — | CN | disclosed |
| CN-108623787-B | Novel conjugated microporous organic polymer and synthesis and application thereof | 浙江工业大学 | 2020-05-26 | — | — | CN | disclosed |