Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290356 | 1.00 | KMT2A (0.43) | KMT2AMEN1ALDH1A1HPGDMCOLN3 | |
| SCHEMBL336604 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL1694151 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL1787921 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL1720326 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL981024 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL981027 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MCOLN3NPC1 | |
| SCHEMBL14991413 | 0.74 | KMT2A (0.50) | KMT2AMEN1ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL14991414 | 0.74 | KMT2A (0.50) | KMT2AMEN1ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL5633933 | 0.73 | MAPT (0.37) | KMT2AMEN1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |