SCHEMBL981024

SCHEMBL981024

O=[N+]([O-])c1cccc(S(=O)(=O)O)c1CC1CO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.41
MEN1 O00255 3/20 0.41
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MCOLN3 Q8TDD5 1/20 0.38
POLB P06746 2/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
F2 P00734 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL336604 1.00 KMT2A (0.41) KMT2AMEN1PRMT5WDR77CA1
SCHEMBL1694151 1.00 KMT2A (0.41) KMT2AMEN1PRMT5WDR77CA1
SCHEMBL1787921 1.00 KMT2A (0.41) KMT2AMEN1PRMT5WDR77CA1
SCHEMBL1720326 1.00 KMT2A (0.41) KMT2AMEN1PRMT5WDR77CA1
SCHEMBL981027 1.00 KMT2A (0.41) KMT2AMEN1PRMT5WDR77CA1
SCHEMBL28290358 0.85 KMT2A (0.43) KMT2AMEN1ALDH1A1MCOLN3POLB
SCHEMBL28290356 0.85 KMT2A (0.43) KMT2AMEN1ALDH1A1MCOLN3POLB
SCHEMBL20502306 0.82 PRMT5 (0.44) KMT2AMEN1PRMT5WDR77ALDH1A1
SCHEMBL28853079 0.82 KMT2A (0.34) KMT2AMEN1PRMT5WDR77ALDH1A1
SCHEMBL28853081 0.82 KMT2A (0.34) KMT2AMEN1PRMT5WDR77ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
EP-3593808-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-12-09 EP claimed
EP-3578185-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-08-05 EP claimed
EP-2687521-B1 \"Process for the enantioselective synthesis of landiolol\ PROCOS SPA (IT) 2015-01-07 EP claimed
WO-2014140220-A1 PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES JANSSEN PHARMACEUTICA, N.V. (BE) 2014-09-18 WO claimed
US-7772334-B2 Crosslinker of reactive functional groups and nonionic metal coordinating structure-containing alkyl or aromatic compound BASF COATINGS GMBH (DE) 2010-08-10 US claimed
US-7759436-B2 Film-former of resin with nonionic metal coordinating structure and crosslinker-reactive group BASF COATINGS GMBH (DE) 2010-07-20 US claimed
WO-2008016199-A1 PROCESS FOR THE PREPARATION OF CHIRAL 2-HYDROXYMETHYL-1,4-BENZODIOXANE COMPOUND AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) 2008-02-07 WO claimed
EP-0930307-B1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO LTD (JP) 2002-12-04 EP claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN disclosed
CN-112105609-A Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors 奥瑞基尼探索技术有限公司 2020-12-18 CN disclosed
CN-108047145-A There is 2- aryl quinoxaline compounds of affinity and preparation method and application with Tau albumen 北京师范大学 2018-05-18 CN disclosed
CN-105228997-B Carm1 inhibitors and uses thereof EPIZYME股份有限公司 2018-03-27 CN disclosed
CN-105452226-B Tetrahydro-and dihydro-isoquinoline PRMT5 inhibitors and uses thereof EPIZYME股份有限公司 2017-09-12 CN disclosed
WO-1996004234-A1 ARYLOXY ANDARYCTHIO PROPANOLAMINE DERIVATIVES USEFUL AS B3-ADRENORECEPTOR AGONISTS AND ANTAGONS OF THE B1 AND B2 ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1996-02-15 WO disclosed
US-5218114-A For treating diseases of gastrointestinal or central nervous systems MERCK & CO., INC. (US) 1993-06-08 US disclosed
EP-0508799-A1 Cholecystokinin antagonists MERCK & CO. INC. (US) 1992-10-14 EP disclosed
US-5084463-A Cardiovascular disorders AMERICAN HOME PRODUCTS CORPORATION (US) 1992-01-28 US disclosed
CN-1055930-A The preparation method of the optically active isomer of the purinyl piperazine derivative that 6-replaces ORTHO PHARMA CORP (US) 1991-11-06 CN disclosed
US-5053338-A Hydrolysis of ester to obtain an optically enriched mixture of a phenol enantiomer GLAXO INC. (US) 1991-10-01 US disclosed