Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23376716 | 0.88 | PSMB5 (0.53) | SYKPPARACTSSCTSLPPARG | |
| SCHEMBL27402880 | 0.86 | SYK (0.52) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL20854198 | 0.85 | SYK (0.54) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL22579840 | 0.85 | SYK (0.54) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL20885281 | 0.85 | SYK (0.54) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL7658308 | 0.85 | SYK (0.54) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL20885274 | 0.85 | SYK (0.54) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL1463134 | 0.84 | POLB (0.58) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL7512116 | 0.84 | POLB (0.58) | SYKPPARAATMCTSSCTSL | |
| SCHEMBL648574 | 0.84 | POLB (0.58) | SYKPPARAATMCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715630-A | β -lactamase inhibitor compounds | 恩塔西斯治疗有限公司 | 2019-05-03 | — | — | CN | disclosed |