SCHEMBL28290522

SCHEMBL28290522

NC(=O)C(=Cc1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.56
CYP1B1 Q16678 1/20 0.54
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
NQO2 P16083 1/20 0.47
KMT2A Q03164 3/20 0.47
CYP3A4 P08684 2/20 0.47
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
EGFR P00533 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
JAK1 P23458 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2836206 0.81 AKR1C1 (0.70) AKR1C3NQO2KMT2ACYP3A4MEN1
SCHEMBL23593943 0.81 AKR1C1 (0.70) AKR1C3NQO2KMT2ACYP3A4MEN1
SCHEMBL6689798 0.81 AKR1C1 (0.70) AKR1C3NQO2KMT2ACYP3A4MEN1
SCHEMBL8830409 0.80 NQO2 (0.63) AKR1C3CES2CES1NQO2KMT2A
SCHEMBL8830412 0.80 NQO2 (0.63) AKR1C3CES2CES1NQO2KMT2A
SCHEMBL30241503 0.80 CTNNB1 (0.53) CYP3A4MAPTF2CYP1A2CYP2C19
SCHEMBL11671064 0.79 AKR1C3 (0.72) AKR1C3CYP1B1CES2CES1KMT2A
SCHEMBL11576396 0.79 AKR1C3 (0.72) AKR1C3CYP1B1CES2CES1KMT2A
SCHEMBL16101600 0.78 MGAM (0.59) KMT2ACYP3A4MEN1KDM4EALDH1A1
SCHEMBL10284967 0.77 PBRM1 (0.54) NQO2KMT2ACYP3A4MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109804033-A Adhesive composition 日本曹达株式会社 2019-05-24 CN disclosed