SCHEMBL28290551

SCHEMBL28290551

C=CC(=O)Cl.O=C1C=CC(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.52
GSK3B P49841 1/20 0.52
CCR6 P51684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL28707868 0.85 GSK3A (0.38) GSK3AGSK3BCCR6
SCHEMBL11637574 0.83 GSK3A (0.55) GSK3AGSK3BCCR6
SCHEMBL11637577 0.83 GSK3A (0.55) GSK3AGSK3BCCR6
Acrylic Acid SCHEMBL380952 0.83 GSK3A (0.55) GSK3AGSK3BCCR6
Acrylic Acid SCHEMBL9443355 0.83 GSK3A (0.55) GSK3AGSK3BCCR6
Acrylic Acid SCHEMBL27596888 0.83 GSK3A (0.55) GSK3AGSK3BCCR6
Acrylamide SCHEMBL9419706 0.81 ALDH1A1 (0.52) GSK3AGSK3BCCR6
Vinyl Chloride SCHEMBL10516224 0.79 GSK3A (0.65) GSK3AGSK3BCCR6
1,1-Dichloroethene SCHEMBL28129640 0.79 GSK3A (0.65) GSK3AGSK3BCCR6
SCHEMBL10867379 0.79 GSK3A (0.65) GSK3AGSK3BCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608379-A A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method 苏州昊帆生物股份有限公司 2019-04-12 CN claimed
CN-109608379-A A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method 苏州昊帆生物股份有限公司 2019-04-12 CN disclosed