Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849251 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL17802484 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL4596001 | 0.78 | ERN1 (0.44) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL29910964 | 0.78 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL6690245 | 0.78 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL6452676 | 0.78 | TDP1 (0.56) | ALDH1A1CYP3A4ALOX15MAPTTDP1 | |
| SCHEMBL29404556 | 0.77 | CYP3A4 (0.42) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL11126763 | 0.75 | TDP1 (0.46) | ALDH1A1CYP3A4ALOX15KDM4EMAPT | |
| SCHEMBL19878494 | 0.75 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15MAPTTDP1 | |
| SCHEMBL1094913 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808075-B | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111704604-B | Preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111808075-A | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111533701-B | Synthetic method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111704604-A | Preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111533701-A | Synthetic method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-110698416-B | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-110698416-A | Preparation method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-109705094-A | A kind of preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2019-05-03 | — | — | CN | disclosed |