Pyridine

Pyridine

SCHEMBL28290649

C1=C(c2ccccc2)NNC1.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
TSHR P16473 2/20 0.35
NAPRT Q6XQN6 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NISCH Q9Y2I1 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ATAD2 Q6PL18 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
NPY5R Q15761 2/20 0.33
AURKA O14965 1/20 0.33
CDK1 P06493 1/20 0.33
LYN P07948 1/20 0.33
PIM1 P11309 1/20 0.33
FGFR1 P11362 1/20 0.33
PRKACA P17612 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972817 0.90 SIGMAR1 (0.39) NISCHALDH1A1MEN1HPGDKMT2A
SCHEMBL15506531 0.76 MEN1 (0.39) NOTUMNISCHMEN1KMT2ANPC1
Biphenyl SCHEMBL126611 0.71 NOTUM (0.77) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL28116352 0.71 NOTUM (0.77) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL27563723 0.71 NOTUM (0.77) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL29136533 0.71 NOTUM (0.77) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL3344340 0.69 NOTUM (0.72) NOTUMTSHRNAPRTTDP1ALDH1A1
Pyridine SCHEMBL27914352 0.69 NOTUM (0.72) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL15052303 0.69 NOTUM (0.72) NOTUMTSHRNAPRTTDP1ALDH1A1
Biphenyl SCHEMBL19412135 0.69 NOTUM (0.72) NOTUMTSHRNAPRTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705018-A Organic compound, organic mixture, composition and organic electronic device 广州华睿光电材料有限公司 2019-05-03 CN disclosed