Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.37 |
| ▸ | PDE9A | O76083 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22298291 | 0.80 | PDE9A (0.42) | KDM5ACHEK1CHEK2PDE9AKDM4C | |
| SCHEMBL22871692 | 0.78 | PDE9A (0.60) | KDM5APDE9A | |
| SCHEMBL20870564 | 0.78 | PDE9A (0.60) | KDM5APDE9A | |
| SCHEMBL23336509 | 0.78 | PDE9A (0.60) | KDM5APDE9A | |
| SCHEMBL4751829 | 0.71 | KDR (0.58) | KDM5APDE9ADRD4 | |
| SCHEMBL28290751 | 0.71 | KDM5A (0.44) | KDM5ACHEK1CHEK2PDE9AKDM4C | |
| SCHEMBL22225310 | 0.65 | PDE9A (0.47) | PDE9A | |
| SCHEMBL17738664 | 0.64 | PSEN1 (0.36) | AOC3DRD4 | |
| SCHEMBL418629 | 0.64 | KDM4E (0.47) | — | |
| SCHEMBL24275785 | 0.63 | PDE9A (0.44) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575016-A | PDE9 inhibitors and uses thereof | 南京药捷安康生物科技有限公司 | 2019-04-05 | — | — | CN | disclosed |