Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.67 |
| ▸ | BRAF | P15056 | 1/20 | 0.66 |
| ▸ | CES1 | P23141 | 1/20 | 0.66 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360592 | 1.00 | KMT2A (0.71) | KMT2ATLR7BRAFCES1GRM4 | |
| SCHEMBL28871752 | 0.88 | TLR7 (0.70) | KMT2ATLR7BRAFCES1GRM4 | |
| SCHEMBL13561074 | 0.87 | KMT2A (0.72) | KMT2AMAPTIDEMAPK1MAPK10 | |
| SCHEMBL4288765 | 0.85 | BRAF (0.57) | KMT2ATLR7BRAFCES1KDR | |
| SCHEMBL5498068 | 0.85 | KMT2A (0.63) | KMT2AGRM4HDAC6KDRMAPT | |
| SCHEMBL7990375 | 0.85 | KDR (0.84) | GRM4HDAC6KDRKCNK3KCNK9 | |
| SCHEMBL15238417 | 0.84 | KMT2A (0.62) | KMT2AKDRMAPTIDEMAPK1 | |
| SCHEMBL28172197 | 0.84 | TLR7 (0.71) | TLR7CES1GRM4MAPTRAB9A | |
| SCHEMBL26657000 | 0.83 | BRAF (0.60) | BRAFGRM4 | |
| SCHEMBL7606537 | 0.82 | KMT2A (0.66) | KMT2AMAPTIDEMAPK1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | claimed |
| CN-109705060-A | A kind of preparation method of N- (2- morpholinyl -5- trifluoromethyl) -2- (3- methylphenoxy) propionamide | 华东理工大学 | 2019-05-03 | — | — | CN | claimed |
| CN-115108978-B | Pyridine formylhydrazine plant antifungal medicine | 西北农林科技大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-109705060-A | A kind of preparation method of N- (2- morpholinyl -5- trifluoromethyl) -2- (3- methylphenoxy) propionamide | 华东理工大学 | 2019-05-03 | — | — | CN | disclosed |