Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.84 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.84 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.84 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.81 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.66 |
| ▸ | MET | P08581 | 1/20 | 0.66 |
| ▸ | MERTK | Q12866 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496401 | 0.90 | GRM4 (1.00) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL2530324 | 0.90 | GRM4 (1.00) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL2528081 | 0.90 | GRM4 (0.72) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL231897 | 0.89 | KDR (0.78) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL29723905 | 0.89 | KDR (0.72) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL30643211 | 0.89 | GRM4 (0.70) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL3087891 | 0.89 | GRM4 (0.70) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL30643208 | 0.89 | KDR (0.72) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL2527967 | 0.89 | GRM4 (0.70) | KDRKCNK3KCNK9GRM4HDAC6 | |
| SCHEMBL28904211 | 0.89 | GRM4 (0.70) | KDRKCNK3KCNK9GRM4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | claimed |
| US-6191146-B1 | BACTERICIDES, FUNGICIDES, VIRICIDES | SMITHKLINE BEECHAM CORPORATION | 2001-02-20 | — | — | US | disclosed |