Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28313648 | 0.89 | TDP1 (0.48) | TDP1LMNAGAAHPGD | |
| Tert-Butyl Formate SCHEMBL28811787 | 0.81 | TDP1 (0.43) | TDP1 | |
| SCHEMBL4660664 | 0.77 | — | — | |
| SCHEMBL4660656 | 0.77 | — | — | |
| SCHEMBL4662119 | 0.77 | — | — | |
| Tert-Butyl Formate SCHEMBL27721997 | 0.77 | TDP1 (0.50) | TDP1LMNAGAAHPGD | |
| Tert-Butyl Formate SCHEMBL28094436 | 0.75 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28110092 | 0.74 | TDP1 (0.56) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27637916 | 0.72 | TDP1 (0.54) | TDP1HPGD | |
| Tert-Butyl Formate SCHEMBL28792406 | 0.71 | TDP1 (0.59) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705501-B | ROR gamma modulators | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |