Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10585007 | 0.92 | THRB (0.53) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL69712 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL27492293 | 0.90 | THRB (0.52) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL28904617 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28562793 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 | |
| Water SCHEMBL29636271 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL28562794 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 | |
| Bromide SCHEMBL4441948 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 | |
| Ammonia Solution, Strong SCHEMBL22612067 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL148456 | 0.90 | THRB (0.55) | THRBTSHRTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263995-B | Surface modification method and surface modification body | 住友橡胶工业株式会社 | 2019-05-28 | — | — | CN | disclosed |