Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27794837 | 0.90 | TDP1 (0.62) | TDP1PTPN5NPC1SMN1; SMN2CYP2C9 | |
| Tert-Butyl Formate SCHEMBL28032597 | 0.88 | TDP1 (0.59) | TDP1PTPN5RAB9ANPC1POLB | |
| Tert-Butyl Formate SCHEMBL28146840 | 0.88 | TDP1 (0.59) | TDP1RAB9ANPC1HPGDSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27502194 | 0.79 | TDP1 (0.43) | TDP1LMNATSHRALDH1A1CES2 | |
| Tert-Butyl Formate SCHEMBL28106695 | 0.78 | TDP1 (0.81) | TDP1TSHRALDH1A1CYP2A6 | |
| Tert-Butyl Formate SCHEMBL27794875 | 0.78 | TDP1 (0.46) | TDP1RAB9ANPC1HPGDSMN1; SMN2 | |
| Formic Acid SCHEMBL28039507 | 0.77 | MEN1 (0.47) | TDP1PTPN5RAB9ANPC1HPGD | |
| SCHEMBL202261 | 0.77 | MAPK1 (0.43) | TDP1PTPN5NPC1SMN1; SMN2MEN1 | |
| Tert-Butyl Formate SCHEMBL28266342 | 0.76 | TDP1 (0.77) | TDP1TSHRALDH1A1 | |
| Tannin Pyrogallol SCHEMBL1419994 | 0.76 | ACHE (0.62) | TDP1RAB9ANPC1HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108906-A | Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate | 临海市华南化工有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-115108906-A | Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate | 临海市华南化工有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-109621863-A | One kind being used for the brominated reaction unit in biphenyl derivatives Bian position and bromination process | 临海市华南化工有限公司 | 2019-04-16 | — | — | CN | disclosed |