SCHEMBL28290879

SCHEMBL28290879

CC(C)OC(=O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA14 Q9ULX7 3/20 0.59
KDM4E B2RXH2 1/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
PDCD1 Q15116 1/20 0.54
CD274 Q9NZQ7 1/20 0.54
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PTPN11 Q06124 2/20 0.49
MAPT P10636 1/20 0.49
GRIN2D O15399 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13229042 0.95 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL707094 0.93 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL7606531 0.88 KDM4E (0.54) CA12CA1CA2CA7CA9
SCHEMBL8041186 0.87 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL23997992 0.86 NPC1 (0.64) CA12CA1CA2CA7CA9
SCHEMBL6653048 0.84 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL30678268 0.84 NPC1 (0.62) CA12CA1CA2CA7CA9
SCHEMBL6233392 0.84 NPC1 (0.62) CA12CA1CA2CA7CA9
SCHEMBL6228537 0.83 CA1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL16687595 0.81 CA12 (0.57) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721490-A The preparation method of 2,6- naphthalenedicarboxylic acid 上野制药株式会社 2019-05-07 CN disclosed