Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859307 | 0.85 | ALDH1A1 (0.50) | PKMPIP4K2AHSD17B10NAMPTPIK3C3 | |
| SCHEMBL19989141 | 0.85 | ALDH1A1 (0.50) | PKMPIP4K2AHSD17B10NAMPTPIK3C3 | |
| SCHEMBL17394167 | 0.81 | PIP4K2A (0.47) | PIP4K2ANAMPTALDH1A1TSHRLMNA | |
| SCHEMBL3024918 | 0.79 | HSD17B10 (0.61) | PKMHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29130948 | 0.79 | HSD17B10 (0.57) | PKMHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14501796 | 0.78 | HSD17B10 (0.60) | HSD17B10ALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL19989429 | 0.77 | ALDH1A1 (0.51) | PKMHSD17B10KIF18AALDH1A1ALOX5AP | |
| SCHEMBL29859296 | 0.77 | ALDH1A1 (0.51) | PKMHSD17B10KIF18AALDH1A1ALOX5AP | |
| SCHEMBL2361303 | 0.77 | ALOX5AP (0.42) | PKMPIP4K2APIK3C3KIF18ACNR1 | |
| SCHEMBL25312484 | 0.77 | MCOLN3 (0.50) | HTR2AHTR2CPKMHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715608-A | The indazole compound used in tendon and/or ligament injury | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |