Trolamine

Trolamine

SCHEMBL28291044

C=CC(=O)OCCN(C)C.OCCN(CCO)CCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.55
HPGD P15428 1/20 0.46
ALDH1A1 P00352 5/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 3/20 0.46
HSD17B10 Q99714 1/20 0.46
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRNB2 P17787 1/20 0.44
CHRM3 P20309 1/20 0.44
CHRNA4 P43681 1/20 0.44
THRB P10828 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 1/20 0.37
DNM1 Q05193 1/20 0.37
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499179 0.89 TSHR (0.70) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL22465822 0.89 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4399489 0.89 TSHR (0.63) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15115 0.89 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL769713 0.87 TSHR (0.61) TSHRHPGDALDH1A1TP53HIF1A
Iodide SCHEMBL1254059 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
Ethylene SCHEMBL8397415 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
Hydrochloric Acid SCHEMBL130714 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28612529 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL1399858 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104246606-B Composite resin composition and application thereof, the method that dental assembly is prepared with stereolithograph 义获嘉伟瓦登特公司 2019-05-10 CN disclosed