SCHEMBL4399489

SCHEMBL4399489

C=CC(=O)OCCN(CCO)CCOC(=O)C=C

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
ALDH1A1 P00352 5/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
HSD17B10 Q99714 1/20 0.52
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.42
MAPK1 P28482 1/20 0.42
THRB P10828 2/20 0.40
KDM4E B2RXH2 2/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22465822 1.00 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL769713 0.98 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16294460 0.92 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7050406 0.92 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10781384 0.90 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
Trolamine SCHEMBL28291044 0.89 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11737404 0.89 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10592028 0.89 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3203187 0.86 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL26944280 0.84 TSHR (0.69) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115232-A ACTINIC RADIATION ROHM AND HAAS COMPANY (US) 1978-09-19 US claimed
EP-3284599-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORP (JP) 2019-07-03 EP disclosed
EP-3284599-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME Fujifilm Corporation (JP) 2018-02-21 EP disclosed
EP-2383118-B1 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP (JP) 2013-10-16 EP disclosed
US-8535857-B2 Dye-containing negative curable composition, color filter, method of producing the same, and solid-state image sensor FUJIFILM CORPORATION (JP) 2013-09-17 US disclosed
US-8535857-B2 Dye-containing negative curable composition, color filter, method of producing the same, and solid-state image sensor FUJIFILM CORPORATION (JP) 2013-09-17 US disclosed
EP-2075632-B1 Dye-containing negative curable composition, color filter, method of producing the same, and solid-state image sensor FUJIFILM CORP (JP) 2011-02-16 EP disclosed
US-7790352-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-09-07 US disclosed
US-7790352-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-09-07 US disclosed
EP-1162245-B1 COATED ARTICLE SDC TECHNOLOGIES ASIA LTD (JP) 2009-12-09 EP disclosed
US-6440568-B1 POLYURETHANE LAYER FORMED ON AT LEAST ONE SIDE OF THE SUBSTRATE AND A SILICON RESIN HARD COAT LAYER ON THE POLYURETHANE LAYER NIPPON ARC CO., LTD. (JP) 2002-08-27 US disclosed
EP-1162245-A1 COATED ARTICLE NIPPON ARC CO., LTD. (JP) 2001-12-12 EP disclosed
US-5963373-A EPOXY, POLYISOCYANATE NIPPON ARC CO., LTD. (JP) 1999-10-05 US disclosed
EP-0922971-A1 PLASTIC LENSES AND PRIMER COMPOSITION USED FOR COATING THE SAME NIPPON ARC CO., LTD. (JP) 1999-06-16 EP disclosed
US-5858077-A Coating composition capable of yielding a cured product having a high refractive index and coated articles obtained therefrom NIPPON ARC CO., LTD. (JP) 1999-01-12 US disclosed
EP-0791636-A1 PRIMER COMPOSITION NIPPON ARC CO., LTD. (JP) 1997-08-27 EP disclosed
US-5654090-A A HARD CURIED FILM ON PLASTIC LENS COMPRISING INORGANIC OXIDE PARTICLES AND ADDITION POLYMER BINDER ANCHORING BY A EPOXY SILICON COMPOUND, CURING AGENTS; DYEABLE, WEATHERPROOFING NIPPON ARC CO., LTD. (JP) 1997-08-05 US disclosed
US-4277319-A N-SUBSTITUTED ACRYOYLOXYETHYLAMINES ROHM AND HAAS COMPANY (US) 1981-07-07 US disclosed
US-4115232-A ACTINIC RADIATION ROHM AND HAAS COMPANY (US) 1978-09-19 US disclosed
US-4001304-A RADIATION CURABLE COATINGS ROHM AND HAAS COMPANY (US) 1977-01-04 US disclosed