Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923788 | 1.00 | MAOB (0.72) | MAOBESR1ESR2OPRM1OPRK1 | |
| SCHEMBL17923791 | 1.00 | MAOB (0.72) | MAOBESR1ESR2OPRM1OPRK1 | |
| SCHEMBL17931596 | 0.89 | MAOB (0.68) | MAOBMAOA | |
| SCHEMBL16552387 | 0.84 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL17923834 | 0.84 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL17931624 | 0.82 | MAOB (0.55) | MAOBESR1ESR2OPRM1OPRK1 | |
| SCHEMBL17935551 | 0.81 | MAOB (0.76) | MAOBMAOA | |
| SCHEMBL17931629 | 0.80 | MAOB (0.49) | MAOBOPRM1OPRK1OPRD1 | |
| SCHEMBL16552344 | 0.79 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL17923867 | 0.79 | MAOB (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574865-A | Monoamine oxidase-B selective depression immunomodulator compounds, its pharmaceutical composition and application | 英属哥伦比亚大学 | 2019-04-05 | — | — | CN | disclosed |