Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17931603 | 0.88 | MAOB (0.46) | MAOBOPRD1OPRK1OPRM1 | |
| SCHEMBL16541165 | 0.82 | MAOB (0.75) | MAOB | |
| SCHEMBL16541163 | 0.82 | MAOB (0.75) | MAOB | |
| SCHEMBL17923788 | 0.80 | MAOB (0.72) | MAOBOPRD1OPRK1OPRM1 | |
| SCHEMBL28291236 | 0.80 | MAOB (0.72) | MAOBOPRD1OPRK1OPRM1 | |
| SCHEMBL17923791 | 0.80 | MAOB (0.72) | MAOBOPRD1OPRK1OPRM1 | |
| SCHEMBL17931630 | 0.78 | MAOB (0.66) | MAOBOPRK1SLC7A5 | |
| SCHEMBL21214549 | 0.77 | OPRM1 (0.52) | OPRD1OPRK1OPRM1 | |
| SCHEMBL17931621 | 0.76 | MAOB (0.48) | MAOBOPRD1OPRK1OPRM1 | |
| SCHEMBL17931598 | 0.72 | MAOB (0.47) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196345-B2 | MAO-B selective inhibitor compounds, pharmaceutical compositions thereof and uses thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2019-02-05 | — | — | US | disclosed |
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-21 | — | — | US | disclosed |
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196345-B2 | MAO-B selective inhibitor compounds, pharmaceutical compositions thereof and uses thereof | MAOB, MAOA, COMT | MAOB 1/4885OPRD1 659/4885OPRK1 234/4885 |
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | MAOB, MAOA, COMT | MAOB 1/4885OPRD1 659/4885OPRK1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.