Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465667 | 0.82 | TSHR (0.56) | MAPTHSD17B10LMNANPSR1HTT | |
| SCHEMBL3627075 | 0.77 | NPC1 (1.00) | NPC1MAPTHSD17B10LMNANPSR1 | |
| SCHEMBL8334105 | 0.76 | MAPT (0.55) | MAPTHSD17B10LMNATSHRESR1 | |
| SCHEMBL27844125 | 0.76 | TSHR (0.61) | MAPTHSD17B10LMNATSHRTDP1 | |
| SCHEMBL27660958 | 0.73 | MAPT (0.48) | MAPTHSD17B10LMNAHTTESR1 | |
| SCHEMBL2834927 | 0.73 | NPC1 (0.82) | NPC1MAPTHSD17B10LMNANPSR1 | |
| SCHEMBL30379936 | 0.72 | ALDH1A1 (0.56) | NPC1MAPTHSD17B10LMNANPSR1 | |
| SCHEMBL950048 | 0.72 | ALDH1A1 (0.56) | NPC1MAPTHSD17B10LMNANPSR1 | |
| SCHEMBL7872643 | 0.72 | NPC1 (0.69) | NPC1MAPTHSD17B10LMNANPSR1 | |
| SCHEMBL28536823 | 0.72 | TSHR (0.50) | NPC1MAPTHSD17B10HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640961-A | Polyalkylene oxides-asparagine enzyme preparation and its preparation and application | 施维雅知识产权英国有限公司 | 2019-04-16 | — | — | CN | disclosed |