Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797344 | 0.86 | KMT2A (0.43) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL4727534 | 0.82 | EPHX1 (0.49) | ALDH1A1KMT2AMEN1KCNA3GAA | |
| SCHEMBL27967317 | 0.79 | KMT2A (0.50) | ALDH1A1SYKKMT2AL3MBTL1KCNA3 | |
| SCHEMBL27820569 | 0.77 | KMT2A (0.41) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL27839967 | 0.77 | KMT2A (0.44) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL28055549 | 0.77 | KMT2A (0.41) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL28055663 | 0.77 | KMT2A (0.41) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL27893654 | 0.77 | KMT2A (0.44) | SYKKMT2AL3MBTL1KCNA3SSTR1 | |
| SCHEMBL28793024 | 0.77 | KMT2A (0.47) | ALDH1A1SYKKMT2AL3MBTL1KCNA3 | |
| SCHEMBL27910784 | 0.77 | SSTR4 (0.41) | SYKKMT2AL3MBTL1KCNA3SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |