SCHEMBL28291441

SCHEMBL28291441

CCCCCCCCC(Cc1ccccc1)C(C)(C)Br

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.53
MMP2 P08253 14/20 0.43
MMP1 P03956 9/20 0.43
MMP3 P08254 9/20 0.43
KCNH2 Q12809 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CNR2 P34972 1/20 0.41
MMP7 P09237 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL640156 0.86 CSNK1E (0.52) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL8382904 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL8386102 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL2788444 0.85 CSNK1E (0.51) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL25287896 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL25283495 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL10451791 0.85 CSNK1E (0.51) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL8382112 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL6651659 0.85 CSNK1E (0.51) CSNK1EMMP2MMP1MMP3KCNH2
SCHEMBL8381675 0.85 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641818-A The dehydrochlorination method of chloralkane 蓝立方知识产权有限责任公司 2019-04-16 CN disclosed