SCHEMBL8386102

SCHEMBL8386102

CCCCCCCCCCCCCCCCCCCCCCC(Cc1ccccc1)C(C)(C)N

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.55
MMP2 P08253 14/20 0.42
MMP1 P03956 9/20 0.42
MMP3 P08254 9/20 0.42
HTR2A P28223 1/20 0.42
KCNH2 Q12809 1/20 0.41
MMP7 P09237 4/20 0.40
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8387575 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8386222 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8382904 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25283495 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL25287896 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8385145 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8382112 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL8381675 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A
SCHEMBL337801 1.00 CSNK1E (0.55) CSNK1EMMP2MMP1MMP3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP claimed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP claimed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO claimed
US-5955584-A NON-PROTEIN ANTIGEN COMPOSED OF STEROID COMPONENT WITH 3 BETA HYDROXY OR 3 KETO GROUP AND QUATERNARY AMMONIUM SALT; FOR THERAPY AND IMMUNOASSAY DIAGNOSIS CHARTER VENTURES (US) 1999-09-21 US disclosed
US-5811248-A Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof CHARTER VENTURES (US) 1998-09-22 US disclosed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP disclosed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP disclosed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO disclosed