Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL9559483 | 0.83 | TP53 (0.61) | TP53CHRM1AKR1A1CHRM3HTR2A | |
| Lactic Acid SCHEMBL27721040 | 0.82 | — | — | |
| Lactic Acid SCHEMBL18393376 | 0.82 | — | — | |
| Lactic Acid SCHEMBL27357663 | 0.82 | — | — | |
| Acetic Acid SCHEMBL5358874 | 0.81 | FFAR3 (0.37) | TP53TDP1CYP2D6CYP2C19ALDH1A1 | |
| Lactic Acid SCHEMBL9569083 | 0.80 | TP53 (0.50) | TP53CHRM1AKR1A1CHRM3HTR2A | |
| Lactic Acid SCHEMBL3928098 | 0.79 | — | — | |
| Lactic Acid SCHEMBL1501503 | 0.79 | TP53 (0.73) | TP53CHRM1AKR1A1CHRM3HTR2A | |
| Lactic Acid SCHEMBL1450479 | 0.79 | TP53 (0.73) | TP53CYP2D6CYP2C19FOLH1 | |
| Lactic Acid SCHEMBL28056896 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531000-B | Use of specific N-methyl-N-acylglucamines in skin cleansers and hand washing detergents | 克拉里安特国际有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-105530995-B | Use of specific N-alkyl-N-acylglucamines in shampoos for conditioning hair | 克拉里安特国际有限公司 | 2019-05-07 | — | — | CN | disclosed |