Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5819597 | 0.86 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL5870799 | 0.86 | — | — | |
| Acetic Acid SCHEMBL4574765 | 0.83 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TDP1 | |
| Lactic Acid SCHEMBL28291471 | 0.81 | TP53 (0.61) | FFAR3TP53CYP2D6CYP2C19ALDH1A1 | |
| Acetic Acid SCHEMBL3042211 | 0.80 | — | — | |
| Acetic Acid SCHEMBL6509092 | 0.79 | FFAR3 (0.37) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL6335654 | 0.78 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL10486550 | 0.77 | FFAR3 (0.47) | FFAR3LCKFYNTP53ALDH1A1 | |
| Acetic Acid SCHEMBL8408056 | 0.76 | FFAR3 (0.54) | FFAR3LCKFYNTP53ALDH1A1 | |
| Acetic Acid SCHEMBL9272509 | 0.76 | FFAR3 (0.54) | FFAR3LCKFYNTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211419-B2 | Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | AJINOMOTO CO., INC. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-20060035343-A1 | Carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | AJINOMOTO CO., INC (JP) | 2006-02-16 | — | — | US | disclosed |
| US-6991924-B2 | Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | AJINOMOTO CO., INC. (JP) | 2006-01-31 | — | — | US | disclosed |
| US-20030129708-A1 | Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | AJINOMOTO CO., INC (JP) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129708-A1 | Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | UMPS, ODC1, GMPS | FFAR3 2949/4885LCK 3345/4885FYN 4343/4885 |
| US-20060035343-A1 | Carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate | UMPS, UPP1, GMPS | FFAR3 2688/4885LCK 3349/4885FYN 4246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.