Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALAD | P13716 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236884 | 0.79 | POLB (0.44) | GPR35DAOPOLBRECQLAPEX1 | |
| SCHEMBL5082936 | 0.77 | TSHR (0.43) | DAOPOLBRECQLAPEX1CASP6 | |
| SCHEMBL14638630 | 0.77 | CYP3A4 (0.47) | DAOPOLBRECQLAPEX1CASP6 | |
| SCHEMBL28209047 | 0.77 | MAPT (0.59) | POLBTDP1TSHRMAPT | |
| SCHEMBL623033 | 0.76 | TSHR (0.52) | GPR35DAOTSHRCES2CES1 | |
| SCHEMBL13268517 | 0.76 | POLB (0.41) | GPR35DAOPOLBRECQLAPEX1 | |
| SCHEMBL1230762 | 0.76 | TDP1 (0.41) | GPR35DAOPOLBRECQLAPEX1 | |
| SCHEMBL8308963 | 0.76 | DPP4 (0.43) | DAOPOLBRECQLAPEX1CASP6 | |
| SCHEMBL1973884 | 0.74 | GPR35 (0.47) | GPR35POLBTDP1L3MBTL1TSHR | |
| SCHEMBL25238207 | 0.74 | GPR35 (0.43) | GPR35POLBCTDSP1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475776-A | For preventing and treating the tricyclic carboxylic acid amides of arthropod | BAYER CROPSCIENCE AG | 2019-11-19 | — | — | CN | disclosed |
| CN-107074874-B | ERK inhibitor | 伊莱利利公司 | 2019-04-23 | — | — | CN | disclosed |
| CN-107074874-A | Erk inhibitor | 伊莱利利公司 | 2017-08-18 | — | — | CN | disclosed |