Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.62 |
| ▸ | CA2 | P00918 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591307 | 0.87 | CA1 (0.61) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL3417705 | 0.87 | CA1 (0.61) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL27438850 | 0.84 | CA1 (0.58) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL1133577 | 0.84 | CA1 (0.58) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL7857929 | 0.84 | CA1 (0.57) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL27716370 | 0.83 | PTPN1 (0.66) | CA1CA2KMT2AKDM4EALDH1A1 | |
| Water SCHEMBL27449135 | 0.83 | CA1 (0.56) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL8154964 | 0.82 | CA1 (0.55) | CA1CA2KMT2AHSD17B10KDM4E | |
| SCHEMBL22349646 | 0.81 | KDM4E (0.58) | CA1CA2KMT2AKDM4EALDH1A1 | |
| SCHEMBL29569597 | 0.80 | CA1 (0.72) | CA1CA2KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225745-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Athenex, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076662-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | ATHENEX, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |