Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591307 | 1.00 | CA1 (0.61) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL3610930 | 0.88 | PTPN1 (0.59) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL28291736 | 0.87 | CA1 (0.62) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL27438850 | 0.87 | CA1 (0.58) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL1133577 | 0.87 | CA1 (0.58) | CA1CA2KDM4EKMT2ACYP3A4 | |
| Water SCHEMBL27449135 | 0.86 | CA1 (0.56) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL27716370 | 0.86 | PTPN1 (0.66) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL8154964 | 0.84 | CA1 (0.55) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL7857929 | 0.83 | CA1 (0.57) | CA1CA2KDM4EKMT2ACYP3A4 | |
| SCHEMBL22349646 | 0.83 | KDM4E (0.58) | CA1CA2KDM4EKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032248-A2 | MULTIFUNCTIONAL ALBUMIN CONJUGATES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-03-25 | — | — | WO | disclosed |
| US-20100029758-A1 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. | 2010-02-04 | — | — | US | disclosed |
| EP-1484966-A4 | DERIVATIVES OF ISOFLAVONES | YEDA RES & DEV (IL) | 2006-04-05 | — | — | EP | disclosed |
| US-20050096381-A1 | Derivatives of isoflavones | YEDA & MEDICAL RESEARCH | 2005-05-05 | — | — | US | disclosed |
| EP-1484966-A2 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003079965-A2 | DERIVATIVES OF ISOFLAVONES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-10-02 | — | — | WO | disclosed |
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | disclosed |
| US-4166862-A | WEIGHT-GAIN PROMOTERS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-09-04 | — | — | US | disclosed |
| US-3949085-A | Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same | CHINOIN GYOGYSZER-ES VEGYESZETI TERMAKEK GYARA RT (HU) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029758-A1 | DERIVATIVES OF ISOFLAVONES | GPER1, ESR1, ESR2 | CA1 3862/4885CA2 3240/4885KDM4E 2987/4885 |
| US-20050096381-A1 | Derivatives of isoflavones | GPER1, ESR2, ESR1 | CA1 2878/4885CA2 1482/4885KDM4E 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.