SCHEMBL28291801

SCHEMBL28291801

Nc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP3A4 P08684 2/20 0.52
LMNA P02545 2/20 0.52
HTR6 P50406 2/20 0.52
MPO P05164 1/20 0.52
CYP2C9 P11712 1/20 0.52
CA2 P00918 6/20 0.50
CA1 P00915 5/20 0.50
CA12 O43570 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 3/20 0.50
AGO2 Q9UKV8 2/20 0.50
USP2 O75604 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA13 Q8N1Q1 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA5B Q9Y2D0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360992 0.89 GAA (0.44) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL11443510 0.88 TSHR (0.45) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL27852260 0.88 TSHR (0.47) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL11444463 0.87 GAA (0.47) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL11437924 0.85 CA2 (0.50) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL552333 0.84 GAA (0.57) TSHRCYP3A4LMNAHTR6MPO
Potassium SCHEMBL31567825 0.83 GAA (0.55) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL28937067 0.83 GAA (0.55) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL10959726 0.82 TSHR (0.45) TSHRCYP3A4LMNAHTR6MPO
SCHEMBL27466636 0.82 CA2 (0.50) TSHRCYP3A4LMNACYP2C9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109735526-A A kind of magnetic immobilized lipase and its application in preparation (R)-(+)-N- acetyl group-methylbenzylamine 浙江工业大学 2019-05-10 CN disclosed