Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218800 | 0.90 | PARP1 (0.40) | HSD17B10HPGDNR1H2NR1H3OPRK1 | |
| SCHEMBL18428250 | 0.90 | NR1H2 (0.43) | HSD17B10HPGDNR1H2NR1H3OPRK1 | |
| SCHEMBL8564945 | 0.89 | NR1H2 (0.41) | HSD17B10HPGDNR1H2NR1H3OPRK1 | |
| SCHEMBL30032926 | 0.87 | NR1H2 (0.43) | HSD17B10HPGDNR1H2NR1H3OPRK1 | |
| SCHEMBL8569713 | 0.86 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL30181867 | 0.86 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23654034 | 0.85 | HSD17B10 (0.45) | HSD17B10HPGDNR1H2NR1H3PREP | |
| SCHEMBL2095212 | 0.85 | HSD17B10 (0.45) | HSD17B10HPGDNR1H2NR1H3PREP | |
| SCHEMBL3789080 | 0.85 | HSD17B10 (0.45) | HSD17B10HPGDNR1H2NR1H3PREP | |
| SCHEMBL1982884 | 0.85 | HSD17B10 (0.45) | HSD17B10HPGDNR1H2NR1H3PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045969-B | A kind of synthetic method of the card than replacing Buddhist nun | 湖南欧亚药业有限公司 | 2019-04-12 | — | — | CN | disclosed |