Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859935 | 0.93 | KDM4E (0.55) | KDM4EALDH1A1MAPTNPSR1ATM | |
| SCHEMBL31528322 | 0.79 | LTA4H (0.46) | KDM4EL3MBTL1KMT2AMEN1POLB | |
| SCHEMBL22328910 | 0.78 | DDR1 (0.49) | DDR1 | |
| SCHEMBL274217 | 0.78 | NR1H2 (0.48) | KDM4EALDH1A1MAPTDDR1 | |
| SCHEMBL15859821 | 0.77 | DDR1 (0.59) | DDR1 | |
| SCHEMBL15859826 | 0.77 | DDR1 (0.59) | DDR1 | |
| SCHEMBL3558415 | 0.77 | DDR1 (0.59) | DDR1 | |
| SCHEMBL3567113 | 0.77 | DDR1 (0.59) | DDR1 | |
| SCHEMBL15948898 | 0.77 | DDR1 (0.59) | DDR1 | |
| SCHEMBL15381987 | 0.77 | DDR1 (0.49) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641893-A | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | 大邱庆北尖端医疗产业振兴财团 | 2019-04-16 | — | — | CN | disclosed |