Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983353 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL28507143 | 0.85 | ALDH1A1 (0.44) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL2027273 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL12357211 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL17991466 | 0.83 | ALDH1A1 (0.45) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL18510055 | 0.82 | ALDH1A1 (0.52) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL18510017 | 0.82 | ALDH1A1 (0.52) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL27495595 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1ATMHPGDTSHRNPC1 | |
| SCHEMBL28565871 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPSR1ATMALPGPPARG | |
| SCHEMBL28030905 | 0.81 | MAPT (0.50) | ALDH1A1NPSR1ATMPPARGHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526903-A | Bisindole maleimide derivative and its preparation method and application | OCEAN UNIV CHINA | 2019-12-03 | — | — | CN | disclosed |
| CN-110218206-A | Bisindole maleimide derivative and its preparation method and application | 中国海洋大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-106083830-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106146475-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2019-05-17 | — | — | CN | disclosed |