Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238088 | 0.86 | KAT6A (0.54) | KAT6AGABRA1GABRB2CLCN2MRGPRX4 | |
| SCHEMBL4876639 | 0.86 | KAT6A (0.50) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL10299401 | 0.84 | KAT6A (0.49) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL6216947 | 0.84 | PARP1 (0.50) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL16951653 | 0.83 | KAT6A (0.48) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL27570629 | 0.83 | CES2 (0.42) | KAT6ACES2BCHECES1MRGPRX4 | |
| Ammonia Solution, Strong SCHEMBL27338721 | 0.82 | PARP1 (0.49) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL4490600 | 0.82 | KAT6A (0.51) | KAT6AGABRA1GABRB2CLCN2CES2 | |
| SCHEMBL24529118 | 0.81 | MRGPRX4 (0.51) | KAT6ACLCN2HTTMRGPRX4MAPT | |
| SCHEMBL19657225 | 0.81 | KAT6A (0.47) | KAT6AGABRA1GABRB2CLCN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557661-B | A kind of preparation method of catalysis of iodine amides compound synthesizing indoline | 湖南大学 | 2019-04-19 | — | — | CN | disclosed |