Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305030 | 0.81 | CYP2C19 (0.44) | ALDH1A1CYP2C19KMT2AMEN1HPGD | |
| SCHEMBL3252117 | 0.81 | CA1 (0.52) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL18378332 | 0.80 | NPC1 (0.46) | ELANEALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL8778749 | 0.78 | HSD17B10 (0.50) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL8906475 | 0.78 | CA1 (0.48) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL750558 | 0.77 | CA2 (0.52) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL30440548 | 0.76 | TAAR1 (0.52) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL29241054 | 0.76 | CA1 (0.47) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL6558824 | 0.76 | HSD17B10 (0.49) | CA1CA2FAAHPRSS1PRSS2 | |
| SCHEMBL18896349 | 0.76 | CA1 (0.47) | CA1CA2FAAHPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | disclosed |